Parkinson's disease (PD) is a progressive neurological disorder that impacts the quality of life significantly, making in-home monitoring of motor symptoms such as Freezing of Gait (FoG) critical. However, existing symptom monitoring technologies are power-hungry, rely on extensive amounts of labeled data, and operate in controlled settings. These shortcomings limit real-world deployment of the technology. This work presents LIFT-PD, a computationally-efficient self-supervised learning framework for real-time FoG detection. Our method combines self-supervised pre-training on unlabeled data with a novel differential hopping windowing technique to learn from limited labeled instances. An opportunistic model activation module further minimizes power consumption by selectively activating the deep learning module only during active periods. Extensive experimental results show that LIFT-PD achieves a 7.25% increase in precision and 4.4% improvement in accuracy compared to supervised models while using as low as 40% of the labeled training data used for supervised learning. Additionally, the model activation module reduces inference time by up to 67% compared to continuous inference. LIFT-PD paves the way for practical, energy-efficient, and unobtrusive in-home monitoring of PD patients with minimal labeling requirements.

FOG affects between 50% and 80% of people with PD (Weiss et al., 2015), and its presence is associated with an increased risk of falls, affecting the quality of life (Moore et al., 2007). When a FOG episode appears, PD patients can present variability in the gait pattern, with a reduction in step length, shuffling steps, trembling of the legs, and total akinesia with a loss of movement of the limbs or trunk (Okuma, 2014). FOG episodes can have a duration of a few seconds (1 second or less for very short episodes and more than 5 seconds for long episodes) and appear more frequently during typical daily-life conditions than during straight walking assessments in clinical and laboratory settings (Okuma, 2014; Nonnekes et al., 2015). FOG assessment involves the identification of the presence (or absence) of FOG episodes and also aims to identify their severity (Mancini et al., 2019). Assessing FOG in the clinical practice is difficult because of the lack of an optimal freezing score, and difficulties related to the clinical assessment often performed on conditions that hinder the appearance of FOG events during evaluation; for example, the assessment is usually made in the ON state, while FOG occurs more often in OFF state (Schaafsma et al., 2003; Mancini et al., 2021). Although the clinical assessment provides relevant indicators for the characterization of FOG, the conditions whereby these are performed do not accurately represent the severity of FOG in daily life (Rahman et al., 2008; Snijders et al., 2008), such as the patients' homes, where FOG events tend to occur more frequently (Nieuwboer et al., 1998).

Freezing of gait (FoG) is a common gait disability in Parkinson's disease, that usually appears in its advanced stage. Freeze episodes are associated with falls, injuries, and psychological consequences, negatively affecting the patients' quality of life. For detecting FoG episodes automatically, a highly accurate detection method is necessary. This paper presents an approach for detecting FoG episodes utilizing a deep recurrent neural network (RNN) on 3D-accelerometer measurements. We investigate suitable features and feature combinations extracted from the sensors' time series data. Specifically, for detecting FoG episodes, we apply a deep RNN with Long Short-Term Memory cells. In our experiments, we perform both user dependent and user independent experiments, to detect freeze episodes. Our experimental results show that the frequency domain features extracted from the trunk sensor are the most informative feature group in the subject independent method, achieving an average AUC score of 93%, Specificity of 90% and Sensitivity of 81%. Moreover, frequency and statistical features of all the sensors are identified as the best single input for the subject dependent method, achieving an average AUC score of 97%, Specificity of 96% and Sensitivity of 87%. Overall, in a comparison to state-of-the-art approaches from literature as baseline methods, our proposed approach outperforms these significantly.